PILOT for The Precision Exercise Regimen for Cancer Care (PERCC) Study

Purpose

This study is designed to evaluate whether a precision exercise regimen is feasible to implement within cancer populations, specifically stage II-III primary lung cancer patients receiving multimodal therapy, and delivered through telehealth.

Conditions

  • NSCLC Stage II
  • NSCLC, Stage III

Eligibility

Eligible Ages
Over 18 Years
Eligible Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Ages 18 and older at time of diagnosis - Patient diagnosed with stage II and III non-small cell lung cancer (NSCLC) - Patient receives either neoadjuvant chemotherapy or immunotherapy and surgery - Patient able to follow direction and complete questionnaires in English or Spanish - Patient agrees to complete the PERCC intervention

Exclusion Criteria

  • Morbidly obese (BMI >40 kg/m2 ) or anorexic (BMI <17.5 kg/m2 ) - Abnormalities on screening physical exam per study physicians or physical therapist to contraindicate participation in exercise program compliance - Alcohol or drug abuse, significant mental or emotional problems that would interfere with compliance (assessed by NCCN Distress Thermometer) - Patient scheduled to receive single modality cancer treatment (unimodal therapy), scheduled to begin treatment within 2 weeks of the pre-treatment clinic visit, or for whom treatment has already started

Study Design

Phase
N/A
Study Type
Interventional
Allocation
N/A
Intervention Model
Single Group Assignment
Primary Purpose
Treatment
Masking
None (Open Label)

Arm Groups

ArmDescriptionAssigned Intervention
Experimental
Precision Exercise Regimen for Cancer Care (PERCC) 		Participants will engage in PERCC starting at least two weeks prior to receiving their first neoadjuvant treatment for lung cancer and continuing until two months after receiving surgical treatment.
  • Other: Precision Exercise Regimen for Cancer Care (PERCC)
    PERCC has exercise modes including basic transfer and calisthenics mobility, aerobic, and resistance exercises, and will be performed in various postures (supine, sitting, standing, and walking) with variable challenges (level walking, bending, inclines, steps, and squatting). Each participant will complete one supervised, home-based exercise training session per week, delivered through telehealth, that will focus on the resistance exercise prescription. Other unsupervised exercise training sessions will focus on the aerobic exercise prescription and will be completed individually

Recruiting Locations

University of Texas Medical Branch at Galveston
Galveston 4692883, Texas 4736286 77555
Contact:
Rebecca Geck, MSN/MPH
409-266-0496
raschaef@utmb.edu

More Details

Status
Recruiting
Sponsor
University of Utah

Study Contact

Thomas Varghese, MD, MS, MBA, FACS
801-581-5311
thomas.varghese@hsc.utah.edu

Detailed Description

This is a pilot study evaluating the feasibility of the Precision Exercise Regimen for Cancer Care (PERCC) intervention in stage II and stage III Non-Small Cell Lung Cancer (NSCLC) patients receiving multimodal therapy at the Huntsman Cancer Institute (HCI) at the University of Utah. Eligible patients will begin the intervention at the pre-treatment clinic visit and continue until approximately two months post-surgery. The PERCC intervention is a virtually supervised home-based exercise program. Participants will engage in exercise starting at least two weeks before receiving their first neoadjuvant treatment for lung cancer and continuing until two months after receiving surgical treatment. The exercise modes will include basic transfer and calisthenics mobility, aerobic, and resistance exercises and will be performed in various postures (supine, sitting, standing, and walking) with variable challenges (level walking, bending, inclines, steps, and squatting).